2015ACS Applied Materials & Interfaces

Effects of Graphene Modification on the Bioactivation of Polyethylene-Terephthalate-Based Artificial Ligaments

Chun-Hui Wang, Zhong-Shang Guo, Fei Pang, Li-Yuan Zhang, Ming Yan, Jin-Hong Yan, Ke-Wen Li, Xiao-Jie Li, Yong Li, Long Bi, Yi-Sheng Han

ACS Applied Materials & Interfaces · 7, 15263-15276 (2015)

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DOI 10.1021/acsami.5b02893

**AI thematic illustration**Concept artwork created for this paper.

Introduction

Graphene-coated PET ligament grafts were compared with uncoated PET. Cell assays indicated enhanced osteogenic responses; histology and mechanical tests in a rabbit model also favoured the coated grafts at the bone interface.

A closer reading

The study links an early cellular response to a mechanical outcome at the bone–graft interface. Those are complementary endpoints. They support an effect in the models tested, while long-term outcomes in humans would require separate evidence.